Hello. I was diagnosed with persistent depressive...

Is it okay to take both effexor and brintellix at the same time ?
No you can't take both of them in the same time because both increase serotonine level which could lead to serotonin syndrom
What are the Symptoms of  serotonin syndrome  ?
Symptoms of  serotonin syndrome often begin within 24 hours , and their severity can vary . Patients may experience anxiety, agitation, restlessness, , and delirium with confusion. Tremor or muscle spasms, muscle rigidity, rapid heart rate, high blood pressure, high body temperature, sweating, shivering, vomiting, and diarrhea may occur
What can you do to increase medication effect ?
you can increase effexor  up to 300mg daily in devided doses and gradually , to reach the maximum effect you need to wait 2-4 weeks
What are the tips to get rid of depression in your case?
In the beginning, I advise you to start the sessions of psychological consultation and cognitive therapy with a psychologist so not aggravate the problem as it is advised in your case not to focus on negative thoughts that cause you to feel sadness and replace mental schemata and spontaneous misconceptions about life with other rational thoughts through which the strengths and weaknesses are expressed
You can also benefit by moving away from what causes discomfort or anxiety, writing negative thoughts, denying them and replacing them with positive ones, avoiding excessive thinking about life matters, accepting the opinions of others without sensitivity, faith and self-confidence and getting rid of negative thoughts that drive you to doubt those around you and that their talk is directed only to you. Practice meditation and sports that help clear the mind, avoid engaging in futile discussions
I also advise you to follow these steps:
Proper nutrition
Family psychological support
avoiding loneliness
Behavioral therapy and daily exercise
Identify your goals and work to achieve them and reach them
Preoccupation with the activities and positive things and away from staing alone
Get close to the family and enjoy with them in life and share their requirements and positive aspects
What are the symptoms of depression?
mood swings
Lack of pleasure and desire to practice hobbies and daily activities
insomnia
Anorexia
isolation
Inactivity and loss of energy
Feeling guilty
Feeling anxious and thinking about suicide
Headaches and loss of focus